Spring Arbor Living Blog

A new study in laboratory animals suggests a promising new avenue for treating Alzheimer's Disease. They were given a medicine that's been around for decades.
Immune globulin, or gamma globulin, is made from purified blood plasma and is normally used to boost the immune system.

Recently, scientists have been exploring its potential as a treatment for Alzheimer's Disease.

The results of these immune globulin experiments have been inconsistent. Researchers from the Mount Sinai School of Medicine in New York thought these inconsistent results were due to variations in how the immune globulin was administered. So they gave their lab mice very small doses intravenously over four weeks.

Researchers say they saw a dramatic slowdown in the animals' cognitive deterioration.

The treatment increases certain immune system components, which may help restore plasticity, the ability of the brain to rewire itself as needed. It may also have a role in reducing the beta amyloid protein deposits in the brain that are characteristic of Alzheimer's Disease.

The results of the study were presented at a scientific meeting called Experimental Biology 2012 in San Diego, California.

VOA News

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If you or someone you know is experiencing any of the signs of Alzheimer’s Disease, please see a doctor. Early diagnosis gives you a chance to seek treatment and come up with a plan for the future.

Memory loss that disrupts daily life
One of the most common signs of Alzheimer's is memory loss, especially forgetting recently learned information. Others include forgetting important dates or events; asking for the same information over and over; relying on memory aides or family members for things they used to handle on their own.

Challenges in solving problems
Some people may experience changes in their ability to develop and follow a plan or work with numbers. They may have trouble following a familiar recipe or keeping track of monthly bills.

Difficulty completing familiar tasks at home
People with Alzheimer's often find it hard to complete daily tasks such as driving to a familiar location, managing a budget at work or remembering the rules of a favorite game.

Confusion with time or place
People with Alzheimer's can lose track of dates, seasons and the passage of time. They may have trouble understanding something if it is not happening immediately. Sometimes they may forget where they are or how they got there.

Trouble understanding visual images and spatial relationships
For some people, having vision problems is a sign of Alzheimer's. They may have difficulty reading, judging distance and determining color or contrast. In terms of perception, they may pass a mirror and think someone else is in the room. They may not realize they are the person in the mirror.

New problems with words in speaking or writing
People with Alzheimer's may have trouble following or joining a conversation. They may stop in the middle of a conversation and have no idea how to continue or they may repeat themselves. They may struggle with vocabulary; have problems finding the right word or call things by the wrong name.

Misplacing things and losing the ability to retrace steps
A person with Alzheimer's disease may put things in unusual places. They may lose things and be unable to go back over their steps to find them again. Sometimes, they may accuse others of stealing. This may occur more frequently over time.

Decreased or poor judgment
People with Alzheimer's may experience changes in judgment or decision-making especially with money.  They may pay less attention to grooming or keeping themselves clean.

Withdrawal from work or social activities
A person with Alzheimer's may start to remove themselves from hobbies, social activities, work projects or sports. They may have trouble keeping up with a favorite sports team or remembering how to complete a favorite hobby.

Changes in mood and personality
The mood and personalities of people with Alzheimer's can change. They can become confused, suspicious, depressed, fearful or anxious. They may be easily upset at home, at work, with friends or in places where they are out of their comfort zone.

If you or someone you love is suffering from any or all of these signs, contact a doctor and visit an assisted living care community with specific Alzheimer’s care options.

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